Connections > Amazon Redshift V2 connection properties > VPC peering between the serverless runtime environment and Amazon Redshift
  

VPC peering between the serverless runtime environment and Amazon Redshift

When you use the serverless runtime environment and if the serverless runtime environment and the Amazon Redshift cluster reside in different VPCs, you need to configure VPC peering.
For more information about configuring VPC peering, see the How-to-Library article: Configure VPC peering between Amazon Redshift clusters